Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Vineatrol
- Development stage
- Preclinical
- Lead developer
- Actichem
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Vineatrol is a standardized botanical extract derived from wine grape shoots (*Vitis vinifera*). It is characterized by a high concentration of stilbenoids, primarily trans-resveratrol and its dimer epsilon-viniferin, along with other polyphenols that may act synergistically. In preclinical studies, Vineatrol has demonstrated significant antiproliferative activity against human colon cancer cells by inducing cell cycle arrest in the early S phase. This effect is mediated through the nuclear redistribution of cyclin A and the subsequent activation of the cyclin A/cyclin-dependent kinase 2 (CDK2) complex. Additionally, Vineatrol has shown potential as a chemosensitizer, markedly enhancing the inhibitory effects of 5-fluorouracil (5-FU) on cancer cell proliferation. It is primarily marketed as a nutraceutical ingredient for its antioxidant and potential health-promoting properties.
- Brand names
- Vineatrol
- Other names
- wine grape shoot extract
02
Targets
CDK2 (Cyclin-dependent kinase 2)CCNA2 (Cyclin A2)
Beyond the preview
Go deeper on Vineatrol.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Vineatrol.