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VIR-2981 is an investigational monoclonal antibody developed by Vir Biotechnology for the prevention of influenza. It specifically targets neuraminidase, a key viral protein that facilitates the release of new influenza viruses from infected cells. The antibody binds to a highly conserved region of neuraminidase present across both influenza A and B strains, providing broad-spectrum activity against all major seasonal and pandemic variants. Preclinical data demonstrate potent in vitro activity against these strains, supporting its potential as a preventive therapy for individuals at high risk for severe influenza illness[1][3][5][7]. VIR-2981 was identified using Vir’s proprietary monoclonal antibody discovery platform.
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