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Virokine Immune Therapeutic
- Development stage
- Preclinical
- Lead developer
- Virothera Pharmaceuticals
- Modality
- DNA Therapeutics → Nucleic Acid Therapeutics, Gene Therapies, RNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
Virokine Immune Therapeutic is a preclinical nucleic acid-based immunotherapy developed by Virothera Pharmaceuticals. The platform utilizes DNA or RNA gene therapy to deliver 'virokines'—viral proteins that have evolved to mimic and modulate host cytokines and chemokines. This specific therapeutic is designed to modulate chemokine receptors, with a focus on C-C chemokine receptor type 5 (CCR5) and receptors expressed on T-regulatory (T-reg) cells. By re-engineering the immune signaling environment, the therapy aims to overcome immune evasion in chronic viral infections like Herpes Simplex Virus type 2 (HSV-2) and to disrupt the immunosuppressive microenvironment in solid tumors such as breast cancer.
- Other names
- Virokine
02
Targets
CCR5 (C-C chemokine receptor type 5)
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