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VIS370 is a monoclonal antibody currently in Phase 1 clinical development by Visterra, a subsidiary of Otsuka Pharmaceutical. It is being investigated for the treatment of various immune-mediated diseases. The specific molecular target and mechanism of action for VIS370 have not been publicly disclosed by the developer. The drug was engineered using Visterra's proprietary Hierotope platform, which utilizes computational and experimental tools to identify and target unique, conserved epitopes on complex proteins that are traditionally difficult to drug, aiming to create highly specific and potent therapeutic candidates.
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