Drug intelligence / Profile preview

vitamin a + vitamin d + vitamin e

Development stage
Unknown
Lead developer
DSM-Firmenich
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral, Intramuscular, Subcutaneous
01

Overview

This is a combination dietary supplement containing three fat-soluble vitamins—vitamin A, vitamin D, and vitamin E. These vitamins are essential micronutrients with distinct but complementary roles in human health. Vitamin A (retinol and related compounds) is crucial for vision, immune function, reproduction, and cellular communication; it acts as an antioxidant and supports epithelial cell integrity[3][6][8]. Vitamin D (commonly cholecalciferol or ergocalciferol) regulates calcium and phosphate metabolism to maintain bone health, muscle function, nerve signaling, and immune response[5]. Vitamin E (tocopherols/tocotrienols) functions primarily as an antioxidant protecting cell membranes from oxidative damage. This combination is used to prevent or treat deficiencies due to poor diet or increased requirements during illness or pregnancy[7]. The mechanism of action involves supplementation of these essential nutrients to restore normal physiological levels.

Brand names
Adeforte BellaAdeforte
02

Targets

TTPA (Alpha-tocopherol transfer protein)VDR (Vitamin D receptor)RAR (Retinoic acid receptor)STRA6 (Stimulated by retinoic acid gene 6 protein)

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