Drug intelligence / Profile preview

vitamin b complex (Merit Pharmaceutical)

Development stage
Unknown
Lead developer
Merit Pharmaceutical
Modality
Small Molecules
Administration
Intramuscular, Intravenous
01

Overview

B-Plex is a sterile injectable vitamin B complex formulation developed by Merit Pharmaceuticals. It contains a combination of essential B vitamins, typically including thiamine (B1), riboflavin (B2), niacinamide (B3), pyridoxine (B6), and dexpanthenol (B5). These vitamins serve as vital precursors for coenzymes involved in numerous metabolic pathways, such as the citric acid cycle and the electron transport chain, which are critical for energy production and cellular maintenance. The product is indicated for the treatment and prevention of vitamin B deficiencies in patients who cannot tolerate oral intake or have severe malabsorption issues, such as those with chronic alcoholism, severe illness, or post-operative recovery needs. By providing these micronutrients parenterally, B-Plex ensures rapid availability for cellular processes, supporting neurological function, skin integrity, and overall metabolic homeostasis.

Brand names
B-PlexB PLEX
Other names
Vitamin B complex injection
02

Targets

PDH (Pyruvate dehydrogenase complex)SDH (Mitochondrial electron transport chain complex II)NADH:ubiquinone oxidoreductase subunit familyTKT (Transketolase)OADHCs (2-oxoacid dehydrogenase complexes)PDXK (Pyridoxal kinase)α-KGDH (Alpha-ketoglutarate dehydrogenase complex)

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