Drug intelligence / Profile preview

vitex simplicifolia extract

Development stage
Preclinical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Vitex simplicifolia extract is a botanical extract obtained from the leaves or dried ripe fruits of Vitex simplicifolia (often considered a variety of Vitex trifolia, known as Vitex trifolia var. simplicifolia), a tropical/subtropical shrub in the Lamiaceae family[2][4]. The extract contains a variety of phytochemicals, notably flavonoid derivatives (such as penduletin and artemetin), triterpenes, and other secondary metabolites[2][4]. Research demonstrates in vitro trypanocidal activity against Trypanosoma brucei rhodesiense, indicating potential as an antitrypanosomal agent, though clinical data are lacking[4]. Like other Vitex species, extracts are investigated for anti-inflammatory, antimicrobial, antioxidant, and cytotoxic properties[1]. Traditional uses may overlap with other Vitex species (such as for menstrual complaints), but such uses are inferred and not directly established for vitex simplicifolia extract.

Other names
vitex simplicifolia leaf extractvitex simplicifoliavitex trifolia var. simplicifolia extract
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

Beyond the preview

Go deeper on vitex simplicifolia extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on vitex simplicifolia extract.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call