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VitroGro ECM
- Development stage
- Phase 3
- Lead developer
- Tissue Therapies
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Devices → Device-based Delivery → Drug Delivery Systems, Recombinant Proteins and Enzymes, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Topical
01
Overview
VitroGro ECM is a topically applied synthetic extracellular matrix (ECM) protein designed as a biomimetic scaffold to promote wound healing. It acts by replacing the degraded native ECM in hard-to-heal wounds and provides a physical structure for cell attachment, which is essential for subsequent cellular functions such as proliferation and migration. The product comprises portions of vitronectin and insulin-like growth factor 1 (IGF-1), mimicking natural components of the human ECM. Its primary indication is for chronic wounds including venous leg ulcers and diabetic foot ulcers. Developed originally by Tissue Therapies Limited (now Factor Therapeutics Limited), VitroGro ECM has been classified as both a biologic product and considered for pharmaceutical development pathways in major regulatory markets[2][3][4][5][6].
- Brand names
- VitroGro ECM
- Other names
- VitroGro ECMVF-001VF001VF 001synthetic extracellular matrix proteinbiomimetic scaffold
02
Targets
αVβ3 (Integrin αVβ3)
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