Drug intelligence / Profile preview

VLN3

Development stage
Preclinical
Lead developer
Valink Therapeutics
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
01

Overview

VLN3 is a discovery-stage bispecific or multispecific antibody-drug conjugate (ADC) being developed by Valink Therapeutics for the treatment of various cancers (pan-cancer). The drug is engineered using Valink's proprietary LiliumX™ discovery platform and V-gate™ approach, which are designed to enable fine-tuned target control and an improved therapeutic index for multispecific ADCs. VLN3 consists of a multispecific antibody backbone conjugated to a cytotoxic payload, intended to deliver the toxin selectively to tumor cells. While the specific molecular targets for VLN3 have not been publicly disclosed, the program represents a next-generation approach to ADC therapy by leveraging multi-antigen targeting to enhance precision and efficacy.

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