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VM-102
- Development stage
- Preclinical
- Lead developer
- ViroMed
- Modality
- Gene Addition/Replacement → Gene Therapies, Gene Silencing → Gene Therapies, Gene Editing → Gene Therapies, Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
VM-102 is a preclinical veterinary cell and gene therapy developed by AGeM Bio for the treatment of advanced cancers in dogs and cats. It utilizes the proprietary AGeM (Advanced Gene-engineered MSCs) platform, which involves the engineering of mesenchymal stem cells (MSCs) using non-viral gene delivery methods. This translational program is designed to leverage the natural tumor-homing capabilities of MSCs to deliver therapeutic payloads directly to the site of advanced and metastatic malignancies. By providing localized delivery of therapeutic agents, VM-102 aims to enhance efficacy while minimizing the systemic toxicity often associated with conventional cancer treatments in companion animals. It serves as the veterinary counterpart to the human-focused AGEM-102 program.
- Other names
- VM-102-AGeMVM102-AGeMVM 102-AGeM
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