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VMD-3866 is a topical gel developed by VM Therapeutics for the treatment of pain caused by chemotherapy-induced peripheral neuropathy (CIPN). It is a new molecular entity classified as an analgesic and functions as a calcium channel antagonist, specifically by blocking certain calcium channels in cutaneous nerve fibers, with the aim of reducing nerve activity and neuropathic pain. The drug is being investigated to address the limited efficacy of current therapies for CIPN, and is intended to be applied topically as a gel[1][4][7].
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