vNKT cellular immunotherapy

vNKT cellular immunotherapy is an investigational cell therapy that utilizes invariant natural killer T (iNKT or vNKT) cells as a form of adoptive cellular immunotherapy. These specialized immune cells possess properties of both T lymphocytes and natural killer (NK) cells, enabling them to recognize and eliminate cancerous or infected cells. The therapy involves isolating, expanding, and potentially modifying these vNKT cells outside the body before infusing them back into the patient to enhance antitumor immune responses. The mechanism of action includes direct cytotoxicity against tumor targets as well as secretion of cytokines such as interferon-gamma (IFN-γ), which can modulate other components of the immune system to further boost antitumor activity[6][3]. This approach is being explored primarily for cancer treatment.