Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
VNPP414
- Development stage
- Preclinical
- Lead developer
- Isoprene Pharmaceuticals
- Modality
- Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules
- Administration
- Intraperitoneal
01
Overview
VNPP414 is a preclinical-stage small molecule being developed by Isoprene Pharmaceuticals as a backup compound. Isoprene Pharmaceuticals identifies itself as a 'Small Molecular Degrader Company' that specializes in the development of non-Cereblon molecular glue degraders. While specific target data for VNPP414 is limited, the company's lead 'VNPP' series assets, such as VNPP433-3β, are designed to target the androgen receptor (AR), its splice variant AR-V7, and MDM2 for the treatment of castration-resistant prostate cancer (CRPC). As a backup compound within this pipeline, VNPP414 is likely intended to function as a molecular glue degrader for similar oncogenic targets in the field of oncology.
- Other names
- VNPP414VNPP-414VNPP 414
02
Targets
AR (Adrenergic receptors)MKNK1 (Mitogen‑activated protein kinase‑interacting serine/threonine-protein kinase 1)AR-V7 (Androgen Receptor Variant 7)
Beyond the preview
Go deeper on VNPP414.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on VNPP414.