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VNS-002 is a preclinical genetic-medicine program from ViaNautis Bio that uses the company’s polyNaut platform to enable targeted delivery of genetic cargos to the conducting airways for the treatment of cystic fibrosis. The program is supported by the Cystic Fibrosis Foundation and focuses on identifying optimal formulation candidates for lung airway delivery. While the exact cargo has not been publicly specified, ViaNautis’ platform is designed to deliver plasmid DNA, mRNA, siRNA, or antisense oligonucleotides using polymer-based nanoparticles engineered for barrier penetration and cell-specific targeting.[3][5][7][1]
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