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VNX004 is a preclinical-stage topical formulation being developed by Vaneltix Pharma for the treatment of bladder pain and general topical pain relief. The drug utilizes alkalinized lidocaine as its active ingredient, a local anesthetic that works by blocking voltage-gated sodium channels to inhibit the conduction of pain impulses. VNX004 leverages the technology and intellectual property of Vaneltix's lead product, Alenura, but adapts the alkalinized lidocaine into novel topical dosage forms for indications both within and beyond urology.
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