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VT-105 refers to two distinct investigational drugs in development: 1. A small molecule TEAD autopalmitoylation inhibitor being studied for its ability to inhibit proliferation and tumor growth in NF2-deficient mesothelioma. This compound acts by selectively inhibiting the autopalmitoylation of TEAD transcription factors, which are key effectors in the Hippo signaling pathway implicated in cancer cell proliferation and survival[1][2][5][8]. 2. A universal influenza vaccine candidate developed by Versatope Therapeutics (in collaboration with Intravacc), designed as a prophylactic vaccine for the prevention of influenza A virus infections. Its mechanism is immunostimulation, aiming to provide broad protection against diverse influenza strains[3][4].
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