Drug intelligence / Profile preview

VT400X

Development stage
Preclinical
Lead developer
Vigeo Therapeutics
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

VT400X is a preclinical-stage monoclonal antibody developed by Vigeo Therapeutics for the treatment of various cancers. It specifically targets PRSS2 (Serine protease 2), a protein often overexpressed in the tumor microenvironment that promotes tumor progression, metastasis, and immune evasion. By inhibiting PRSS2, VT400X aims to disrupt these pro-tumorigenic pathways and enhance anti-tumor immune responses. The drug is part of Vigeo's pipeline focusing on novel targets within the tumor microenvironment to overcome resistance to current therapies.

02

Targets

CD36 (CD36 antigen)CD47 (Cluster of Differentiation 47)PRSS2 (Trypsin-2)

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