Drug intelligence / Profile preview

VTRU100

Development stage
Preclinical
Lead developer
VITRUVIAE
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
01

Overview

VTRU100 is an investigational Fc fusion protein being developed by Vitruviae, currently in the discovery stage. It is designed using a proprietary platform that targets specific cancer-associated sugars (glycans) and lipids that are uniquely present or enriched on the surface of malignant cells and cancer stem cells. Although the platform is primarily oncology-focused, VTRU100 is being specifically developed for the treatment of Cytomegalovirus (CMV) infection. The drug functions by binding to these unique glycan and lipid signatures on the surface of infected cells and utilizing its Fc domain to trigger immune effector mechanisms, such as antibody-dependent cellular cytotoxicity (ADCC), to eliminate the targeted cells.

02

Targets

CA19-9 (Carbohydrate antigen 19-9)

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