Drug intelligence / Profile preview

VTx-004

Development stage
Discontinued
Lead developer
VectorY Therapeutics
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intrathecal, Intravenous
01

Overview

VTx-004 is a vectorized antibody drug candidate that targets alpha-synuclein, a protein implicated in the pathogenesis of Parkinson's disease and other synucleinopathies. The drug was initially developed by VectorY BV. Its mechanism of action involves inhibition of alpha-synuclein, aiming to reduce or prevent the aggregation and toxicity associated with this protein in neurodegenerative diseases. As of the latest available information, development of VTx-004 has been discontinued[1][4].

02

Targets

SNCA (Alpha-synuclein)

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