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Vue63 is a preclinical-stage small molecule therapeutic being developed by 1Up Therapeutics for the treatment of liver cancer, specifically hepatocellular carcinoma (HCC). The compound was identified through the company's discovery platform, which leverages genomic and molecular profiling to identify and target specific drivers of liver cancer progression. 1Up Therapeutics focuses on addressing high-risk molecular subtypes of the disease that are often resistant to current standard-of-care treatments. As of 2024, Vue63 remains in early development, and while its specific molecular target has not been publicly disclosed, it is part of a pipeline aimed at "undruggable" targets in the liver cancer landscape.
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