Drug intelligence / Profile preview

VX-A903-2

Development stage
Preclinical
Lead developer
VERAXA Biotech
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

VX-A903-2 is a discovery-stage bispecific T-cell engager (BiTAC-TCE) being developed by VERAXA Biotech for the treatment of solid tumors, including lung cancer, colon cancer, and pancreatic cancer. The drug candidate is part of VERAXA's proprietary BiTAC (Bi-targeted Tumor-Associated Cytotoxicity) platform, which is designed to create next-generation cancer therapies with improved safety and efficacy profiles. VX-A903-2 functions by simultaneously binding to a tumor-associated antigen and the CD3 receptor on T cells, thereby recruiting and activating T cells to induce targeted cytotoxicity against tumor cells. As of the current pipeline information, the specific tumor-associated targets for VX-A903-2 have not been publicly disclosed.

02

Targets

CD3 (T-cell surface glycoprotein CD3)

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