Drug intelligence / Profile preview

Wakansen

Development stage
Unknown
Lead developer
Rohto Pharmaceutical
Administration
Oral
01

Overview

Wakansen is a brand of traditional Japanese Kampo (herbal) medicines developed and marketed by Rohto Pharmaceutical. Launched in 2006, the product line consists of various classical herbal formulations adapted for modern over-the-counter (OTC) use in Japan. The most prominent product in the series is the Bofutsushogyosan formulation, which is indicated for the treatment of obesity, abdominal fat, and associated symptoms such as constipation and hypertension-related edema. Other products in the Wakansen line include Keigairengyoto for sinus and skin conditions, Shakuyakukanzoto for muscle cramps, and Goshajinkigan for lower body pain and numbness. These medicines are typically formulated as tablets or granules for oral administration and are regulated as pharmaceutical products (specifically Second-class OTC drugs) in Japan.

Brand names
Wakansen
Other names
和漢箋
02

Targets

EAAT3 (Excitatory amino acid transporter 3)HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))HTR2A (Serotonin receptor 5-HT2A)GABRA2 (Gamma-aminobutyric acid receptor subunit alpha 2)GLUT5 (Solute carrier family 2, facilitated glucose transporter member 5)

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