Drug intelligence / Profile preview

walnut protein flour

Development stage
Phase 2
Lead developer
UNC School of Medicine
Modality
Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Walnut Protein Flour is an investigational allergen product used in oral immunotherapy (OIT) for the treatment of tree nut allergies. Developed by researchers at the University of North Carolina at Chapel Hill, the therapy involves the daily ingestion of incrementally increasing doses of walnut protein. This process is designed to induce clinical desensitization by modulating the patient's immune response, thereby increasing the threshold for allergic reactions upon accidental exposure to walnuts. The treatment also aims to provide cross-desensitization to other related tree nuts by leveraging shared allergenic epitopes.

Other names
Walnut Oral ImmunotherapyWalnut OIT
02

Targets

IgE (Immunoglobulin E)

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