Drug intelligence / Profile preview

Wantong Jinggu Babao plaster

Development stage
Phase 3
Lead developer
Tonghua Wantong Pharmaceutical
Administration
Topical
01

Overview

Wantong Jinggu Babao plaster is a traditional Chinese medicine (TCM) topical formulation developed by Tonghua Wantong Pharmaceutical. It is specifically designed for the treatment of pain-predominant shoulder periarthritis (adhesive capsulitis), particularly for patients presenting with the TCM pattern of wind-cold obstructing collaterals. The plaster is a multi-ingredient herbal product intended to alleviate pain and improve joint mobility by expelling wind, dissipating cold, and unblocking the collaterals. It is currently being evaluated in a randomized, double-blind, placebo-controlled Phase 3 clinical trial in China to assess its efficacy and safety in this patient population.

Brand names
Wantong Jinggu Babao plaster
Other names
万通筋骨八宝膏
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TRPA1 (Transient receptor potential cation channel subfamily A member 1)TRPM8 (Transient receptor potential cation channel subfamily M member 8)TRPV1 (Transient receptor potential cation channel subfamily V member 1)NaV (Voltage-gated sodium channels)Glycine receptor

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