Drug intelligence / Profile preview

water-soluble tomato concentrate

Development stage
Unknown
Lead developer
Provexis
Modality
Small Molecules
Administration
Oral
01

Overview

Water-soluble tomato concentrate (WSTC) is a natural extract derived from ripe tomatoes (*Lycopersicon esculentum*) by removing fat-soluble components and insoluble material. It is substantially free of lycopene and primarily contains compounds such as adenosine, chlorogenic acid, and rutin[3][4]. WSTC has demonstrated antiplatelet effects by inhibiting ADP- or collagen-induced platelet activation and aggregation in vitro and in vivo[4][5]. Clinical studies have shown that supplementation with WSTC can lower blood pressure, improve cardiovascular risk profiles in hypercholesterolemic individuals, reduce plasma triglyceride levels, and modulate inflammatory responses[1][2][3]. Its mechanism of action involves the inhibition of platelet function through multiple pathways without significantly increasing bleeding risk. The product is marketed under the brand name Fruitflow.

Brand names
Fruitflow
Other names
water-soluble tomato extractWSTCWTE
02

Targets

P4HB (Protein disulfide-isomerase)P2Y12 (Purinergic P2Y12 receptor)CD36 (CD36 antigen)GPIIb/IIIa (Integrin alpha-IIb/beta-3)

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