Drug intelligence / Profile preview

WE

Development stage
Preclinical
Lead developer
JW Theriac Pharmaceutical
Modality
Small Molecules
01

Overview

WE is an undisclosed **small-molecule dual inhibitor of Wee1 and Myt1** being developed by **JW Theriac** for **cancer**. The program appears on the company's pipeline as a **preclinical** oncology asset. By simultaneously inhibiting the cell-cycle checkpoint kinases Wee1 and Myt1, the molecule is intended to disrupt checkpoint control and force tumor cells through aberrant mitotic progression, a strategy consistent with targeted anticancer therapy.

Other names
JW Theriac Pharmaceuticals Wee1 Myt1 small molecule CancerWee1 Myt1 dual inhibitorWee-1 Myt1 dual inhibitorWee 1 Myt1 dual inhibitor
02

Targets

PKMYT1 (Protein kinase membrane associated tyrosine/threonine 1)WEE1 (WEE1 G2 checkpoint kinase)

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