Drug intelligence / Profile preview

Weifuchun Capsules

Development stage
Unknown
Lead developer
Huqing Yutang
Administration
Oral
01

Overview

Weifuchun Capsules is a Chinese Patent Medicine (CPM) widely used in China for the treatment of chronic atrophic gastritis (CAG) and gastric precancerous lesions (GPL), such as intestinal metaplasia and low-grade intraepithelial neoplasia. The formulation typically consists of three main herbal components: *Rabdosia rubescens* (Dong Ling Cao), *Isatis indigotica* (Ban Lan Gen), and *Poria cocos* (Fu Ling). It is developed and manufactured by Huadong Medicine. The therapeutic mechanism involves strengthening the spleen, tonifying qi, and resolving blood stasis according to Traditional Chinese Medicine principles. Clinically, it is observed to improve gastric mucosal atrophy, reduce inflammation, and potentially lower the risk of progression to gastric cancer by modulating biomarkers like pepsinogen and gastrin, and regulating the expression of oncostatin M.

Brand names
Weifuchun
Other names
Weifuchun Jiaonang
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)KPNA2 (Karyopherin subunit alpha-2)TLR2/CD14 (Toll-like receptor 2/Monocyte differentiation antigen CD14 complex)PLA2G1B (Phospholipase A2 group IB)

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