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wenyang yishen tongluo decoction
- Development stage
- Preclinical
- Lead developer
- Yunnan Provincial Hospital of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Wenyang Yishen Tongluo Decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by the Yunnan Hospital of Traditional Chinese Medicine (also known as the First Affiliated Hospital of Yunnan University of Traditional Chinese Medicine). The decoction is specifically formulated to treat rheumatoid arthritis (RA), particularly cases classified under the TCM syndromes of 'Wind-Cold-Dampness Bi Syndrome' or 'Cold Type' RA. Its therapeutic rationale is based on the principles of warming yang (Wenyang), tonifying the kidney (Yishen), and dredging the collaterals (Tongluo) to alleviate joint pain, swelling, and stiffness. Clinical research is also exploring its efficacy in treating RA-associated osteoporosis, suggesting a potential role in modulating bone metabolism and reducing systemic inflammation.
- Brand names
- Wen Yang Yi Shen Tong Luo Formula
- Other names
- Wenyang Yishen Tongluo FormulaWenyang Yishen Tongluo PrescriptionWen Yang Yi Shen Tong Luo FormulaWenyang Yishen Tongluo Decoction
02
Targets
BAX (Apoptosis regulator BAX)IL-6 (Interleukin 6)CASP3 (Caspase-3)
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