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WenyangJianpi-qushi Decoction is a traditional Chinese medicine (TCM) herbal formula used primarily for the treatment of conditions characterized by "spleen deficiency and dampness accumulation" according to TCM theory. It is typically prepared as a decoction—a method where multiple herbs are boiled together to extract their active compounds. The formula is individualized and may be modified based on patient presentation, but its core function is to warm yang, strengthen the spleen, and dispel dampness. Recent clinical research has evaluated its use in combination with mometasone furoate cream for atopic dermatitis of the spleen deficiency and dampness type, showing significant efficacy in reducing disease severity scores (SCORAD), serum IgE levels, peripheral blood eosinophil counts, recurrence rates, and improving overall response rates compared to standard therapy alone[1]. The mechanism of action involves multi-target modulation typical of TCM formulas; it likely exerts immunomodulatory effects—reducing inflammation and allergic responses—though precise molecular targets are not fully elucidated.
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