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Wenzhen Yunqi Decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by researchers at Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, affiliated with the Shanghai University of Traditional Chinese Medicine. It is primarily investigated for the treatment of chronic fatigue syndrome (CFS). The formula is designed based on the 'Wu Yun Liu Qi' (Five Movements and Six Qi) theory, a classical TCM framework that incorporates astronomical and meteorological factors into disease diagnosis and treatment. In clinical research, Wenzhen Yunqi Decoction is evaluated for its efficacy in improving fatigue symptoms and its impact on various physiological markers, including the hypothalamic-pituitary-adrenal (HPA) axis, immune system indices, intestinal microbiota composition, and brain functional network connectivity. It is often studied as part of a syndrome-based precise intervention strategy alongside other TCM formulas.
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