Drug intelligence / Profile preview

wheat bran with reduced particle size

Development stage
Preclinical
Modality
Microbiome Therapeutics
Administration
Oral
01

Overview

Wheat bran with reduced particle size, also known as micronized or fine wheat bran, is a processed form of wheat bran, the outer layer of the wheat kernel, where the particle size has been significantly decreased through mechanical means such as superfine grinding. This modification aims to enhance its functional properties, including sensory attributes in food products, and potentially improve its bioavailability and physiological effects. It is a rich natural source of dietary fiber (both insoluble and soluble), protein, B vitamins, iron, and various phytonutrients like antioxidants, phenolic acids, and phytosterols. Its primary mechanism of action involves its high fiber content, which contributes to increased stool bulk and accelerated intestinal transit, thereby alleviating constipation and supporting overall digestive health. The reduced particle size can also increase its fermentability by gut microbiota, leading to enhanced production of beneficial short-chain fatty acids. Additionally, it possesses antioxidant properties due to its phytonutrient content. It is widely used as a dietary supplement and functional food ingredient to promote gastrointestinal well-being and may offer benefits in managing conditions such as irritable bowel syndrome, high cholesterol, and blood pressure.

Brand names
Shiloh Farms Fine Wheat Bran
Other names
micronized wheat branfine wheat bran

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