Drug intelligence / Profile preview

wheat gluten hydrolysate

Development stage
Preclinical
Lead developer
Archer Daniels Midland
Modality
Peptides, Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Wheat gluten hydrolysate is a mixture of bioactive peptides and amino acids produced through the enzymatic hydrolysis of wheat gluten. It is distinguished by an exceptionally high concentration of L-glutamine, typically comprising approximately 30% of its total amino acid profile. In the fields of sports nutrition and clinical health, it is utilized to support muscle protein synthesis, accelerate recovery following strenuous exercise, and maintain intestinal barrier integrity. Beyond its nutritional value, wheat gluten hydrolysate has been studied for its potential therapeutic effects, including the inhibition of Angiotensin-Converting Enzyme (ACE) and Dipeptidyl Peptidase 4 (DPP4), which suggest applications in managing hypertension and glycemic control. It is primarily manufactured by food science and ingredient companies as a highly soluble and absorbable alternative to intact wheat protein.

Brand names
Glutamine PeptidesHWG
Other names
hydrolyzed wheat glutenwheat protein hydrolysatehydrolyzed wheat proteinWGH
02

Targets

ACE (Angiotensin Converting Enzyme)

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