Drug intelligence / Profile preview

wheat peptides + fucoidan

Development stage
Unknown
Lead developer
Amway
Modality
Peptides
Administration
Oral
01

Overview

Wheat peptides + fucoidan is a combination of two food-grade bioactive ingredients, wheat-derived peptides and fucoidan (a sulfated polysaccharide from brown seaweed), developed as a nutritional supplement. This combination has demonstrated protective effects against gastric mucosal damage in both animal models and human clinical trials. Mechanistically, it acts through anti-oxidant, anti-inflammatory, and pro-survival pathways. In preclinical studies, the combination increased superoxide dismutase levels (anti-oxidant effect), decreased malondialdehyde (marker of oxidative stress), reduced inflammatory mediators such as interleukin-8 and platelet-activating factor, suppressed apoptosis via Caspase 3 reduction, and promoted mucosal healing by increasing prostaglandin E2 and activating epidermal growth factor receptor signaling[1][3]. Clinical trials in patients with chronic superficial gastritis showed that supplementation reduced gastric mucosal damage, improved gastrointestinal symptoms (pain, bloating, acid reflux), enhanced quality of life scores[2], decreased fecal calprotectin (an inflammation marker), slightly increased short-chain fatty acids production in the gut microbiota[2], and shifted gut microbial composition toward more beneficial taxa such as Bifidobacterium pseudocatenulatum[6]. The product is positioned as a dietary supplement for supporting gastric health.

Other names
WPF
02

Targets

IL8 (C-X-C Motif Chemokine Ligand 8)PTAFR (Platelet-activating factor receptor)PGE2 (Prostaglandin E2)CASP3 (Caspase-3)EGFR (Epidermal growth factor receptor)

Beyond the preview

Go deeper on wheat peptides + fucoidan.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on wheat peptides + fucoidan.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call