Drug intelligence / Profile preview

wheatgrass juice

Development stage
Unknown
Lead developer
Rambam Health Care Campus
Administration
Oral
01

Overview

Wheatgrass juice (WGJ) is a nutritional supplement extracted from the young sprouts of the common wheat plant, *Triticum aestivum*. It is characterized by high concentrations of chlorophyll, amino acids, minerals, vitamins, and enzymes. In clinical research conducted at the Rambam Health Care Campus (notably trial NCT01991080), WGJ has been investigated as a supportive therapy for patients with stage II-III colorectal cancer receiving adjuvant chemotherapy (such as capecitabine or 5-fluorouracil with oxaliplatin). The juice is hypothesized to exert anti-inflammatory and immunomodulatory effects by influencing cytokine profiles (e.g., IL-6, IL-8, IL-10, and IL-12) and may help reduce chemotherapy-induced myelotoxicity, potentially improving patient quality of life and treatment adherence.

Other names
wheatgerm juiceWGJTriticum aestivum juice
02

Targets

IL10 (Interleukin-10)IL8 (C-X-C Motif Chemokine Ligand 8)IL-6 (Interleukin 6)IL12 (Interleukin-12)

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