Drug intelligence / Profile preview

white soft paraffin

Development stage
Unknown
Lead developer
Unilever
Modality
Small Molecules
Administration
Topical
01

Overview

Vaseline Pure, developed by NI-THE Pharmaceuticals, is a topical emollient formulation of white soft paraffin (also known as white petrolatum). It is a purified mixture of semi-solid hydrocarbons that functions as an occlusive agent. When applied to the skin, it forms a hydrophobic barrier on the stratum corneum, which significantly reduces transepidermal water loss (TEWL). This physical mechanism helps to retain moisture within the skin, making it highly effective for managing dry skin conditions, protecting minor wounds, and soothing irritated dermatological areas. As a chemically inert substance, it is widely used in dermatology for its high tolerability and lack of biological interaction with skin cells.

Brand names
Vaseline Pure
Other names
White PetrolatumPetrolatumWhite Soft Paraffin

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