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Whole blood transfusion is a medical procedure involving the administration of human blood that has not been separated into its individual components, such as red blood cells, plasma, and platelets. In the context of research led by **Oregon Health and Science University (OHSU)**, whole blood is being investigated for its efficacy in treating patients with **traumatic brain injury (TBI)**, intracranial hemorrhage, and anemia. Unlike standard component therapy, which delivers blood elements separately, whole blood provides these components in a physiological ratio. This approach is hypothesized to better restore volume, improve oxygen-carrying capacity, and provide essential coagulation factors and platelets to promote hemostasis, potentially improving clinical outcomes in patients with severe hemorrhagic brain injuries.
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