Drug intelligence / Profile preview

WIGLD

Development stage
Preclinical
Lead developer
Fukuyama University
01

Overview

WIGLD: sourced facts only. name: "These findings suggested that the injectable WIGLD formulation, with its potent anti-HMGB1 activity, represents a promising therapeutic strategy for managing ICH-related brain edema and associated injuries." [PMID:40268479]; target: "These findings suggested that the injectable WIGLD formulation, with its potent anti-HMGB1 activity, represents a promising therapeutic strategy for managing ICH-related brain edema and associated injuries." [PMID:40268479]; developer: "Department of Pharmacotherapeutics, Graduate School of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 985-1, Sanzo, Higashimura-cho, Fukuyama, Hiroshima 729-0292, Japan." [PMID:40268479]; stage: "Thus, we investigated the therapeutic efficacy of an intravenously injected solubilized WIGLD formulation in a murine model of ICH induced by intrastriatal collagenase injection." [PMID:40268479]

02

Targets

HMGB1 (High mobility group protein B1)

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