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wild douc fecal microbiota transplant
- Development stage
- Preclinical
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral, Rectal
01
Overview
Wild douc fecal microbiota transplant refers to the experimental transfer of gut microbiota from wild red-shanked doucs (*Pygathrix nemaeus*) into a recipient, typically germ-free mice in a research setting. This procedure is used to study the metabolic and protective effects of ancestral or non-industrialized microbiomes. Research indicates that the microbiome of wild primates, which is high in diversity and adapted to high-fiber diets, can prevent weight gain and metabolic shifts associated with Westernized diets when transplanted into animal models. This research aims to understand the link between microbiome loss and the rise of obesity and diabetes in industrialized societies.
- Other names
- wild red-shanked douc fecal microbiota transplantwild primate fecal microbiota transplant
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