Drug intelligence / Profile preview

WJ22096

Development stage
Phase 2
Lead developer
Nanjing Jingao Biomedical Technology
Modality
Small Molecules
Administration
Oral
01

Overview

**WJ22096** is an investigational small molecule inhibitor of focal adhesion kinase (FAK) developed by Nanjing Jingao Biomedical Technology Co., Ltd. for the treatment of advanced solid tumors. Administered orally as tablets once daily after meals, it is being evaluated in a Phase I/II trial (NCT07253116) assessing safety, tolerability, pharmacokinetics, and preliminary efficacy in patients with advanced solid tumors refractory to standard therapies, including non-small cell lung cancer (NSCLC, prioritizing KRAS G12C mutations), colorectal cancer (CRC), and pancreatic cancer. The trial includes dose escalation, expansion, and efficacy cohorts to determine the recommended Phase 2 dose (RP2D).

02

Targets

FAK (Focal adhesion kinase)

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