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WO533 is an investigational **lactic acid-containing vaginal suppository** developed by Dr. August Wolff for local vaginal administration in postmenopausal women with vulvovaginal atrophy. It was evaluated in a prospective, open-label, single-center clinical study assessing efficacy and tolerability in vulvovaginal atrophy. The product is intended to provide local lactic acid exposure and support an acidic vaginal environment; no specific receptor-mediated molecular target has been publicly disclosed. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04222647))
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