Drug intelligence / Profile preview

Wong To Yick Wood Lock Medicated Balm

Development stage
Unknown
Lead developer
Wong To Yick
Modality
Small Molecules
Administration
Topical
01

Overview

Wong To Yick Wood Lock Medicated Balm (also known as Wong To Yick Wood Lock Medicated Oil or 黃道益活絡油) is a traditional Chinese medicated oil formulated for external use to temporarily relieve minor aches, pains, and swelling associated with muscle soreness, joint pain, sprains, bruises, backache, and rheumatism. Developed by Wong To Yick, the formulation contains active ingredients including methyl salicylate, menthol, camphor, and turpentine oil, along with other traditional Chinese herbal extracts. It exerts its therapeutic effects through a combination of counterirritation, vasodilation, and anti-inflammatory actions. Specifically, methyl salicylate acts as a topical nonsteroidal anti-inflammatory drug (NSAID) by inhibiting cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, while menthol and camphor stimulate cold- and heat-sensitive transient receptor potential (TRP) channels (such as TRPM8, TRPV1, and TRPV3) to induce cooling and warming sensations that modulate pain signaling.

Brand names
Wong To Yick Wood Lock Medicated BalmWong To Yick Wood Lock Medicated OilWood Lock Medicated BalmWood Lock Medicated Oil
Other names
黃道益活絡油
02

Targets

TRPA1 (Transient receptor potential cation channel subfamily A member 1)TRPM8 (Transient receptor potential cation channel subfamily M member 8)TRPV1 (Transient receptor potential cation channel subfamily V member 1)TRPV3 (Transient receptor potential vanilloid subtype 3)PGHS-1 (Prostaglandin G/H Synthase 1)

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