Drug intelligence / Profile preview

wu zi ding chuan wen fei hua tan tang

Development stage
Unknown
Lead developer
Beijing University of Chinese Medicine
Administration
Oral
01

Overview

Wu Zi Ding Chuan Wen Fei Hua Tan Tang is a Traditional Chinese Medicine (TCM) herbal decoction formulated to treat respiratory conditions characterized by "Cold-Phlegm" obstructing the lungs, such as chronic obstructive pulmonary disease (COPD), bronchial asthma, and chronic bronchitis. The formula is a specific modification of the classic Wu Zi Ding Chuan Tang, incorporating the "Five Seeds" (typically Perilla, Radish, White Mustard, Bitter Almond, and Descurainia seeds) to descend lung qi and resolve phlegm. It is further enhanced with warming agents like dried ginger and asarum to address underlying cold patterns and improve fluid metabolism in the respiratory tract. Clinical research in China, often conducted in hospital settings, suggests that the decoction can reduce airway inflammation, improve pulmonary function, and alleviate symptoms like wheezing and excessive sputum production during acute exacerbations.

Other names
五子定喘温肺化痰汤Wuzidingchuan Wenfeihuatan DecoctionWu Zi Ding Chuan Wen Fei Hua Tan Formula
02

Targets

mAChR (Muscarinic acetylcholine receptors)ADRB2 (β2)

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