Drug intelligence / Profile preview

Wu Zi Yan Zong Pill

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Wu Zi Yan Zong Pill is a traditional Chinese medicine (TCM) herbal formula used primarily to support male reproductive health and treat male infertility. The name translates as "five seeds passing on the generations," reflecting its composition of five key botanical ingredients. In TCM theory, it is believed to tonify the kidney and nourish Jing (reproductive essence), addressing symptoms such as lower back pain, dribbling urination after micturition, seminal emission, premature ejaculation, impotence and sterility associated with kidney deficiency. Modern research suggests that it may improve sperm concentration and motility in men with oligoasthenozoospermia or other abnormal sperm parameters[1][2][4][6][8]. The classic formulation includes Lycium barbarum fruit (Gou Qi Zi), Cuscuta chinensis seed (Tu Si Zi), Rubus chingii fruit (Fu Pen Zi), Plantago asiatica seed (Che Qian Zi), and Schisandra chinensis fruit (Wu Wei Zi)[2][3][6]. It is widely manufactured in China under cGMP standards for both domestic use and export.

Brand names
FertifruitsMeridian Classic TeapillsYoungain
Other names
Wuzi Yanzong WanFive Seed Prodigy Pill五子衍宗丸
02

Targets

NF-κBESR1 (ERα)CatSperAKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)AHR (Aryl hydrocarbon receptor)CYP17A1 (Steroid 17-alpha-hydroxylase/C17,20 lyase)AR (Adrenergic receptors)

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