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Wuhan Univ. ERα compound 17e
- Development stage
- Preclinical
- Lead developer
- Wuhan University
- Modality
- PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules
01
Overview
Wuhan Univ. ERα compound 17e: sourced facts only. name: "In this regard, we developed and studied a novel ERα degrader, which is a PROTAC-like SERD named 17e." [PMID:36905762]; target: "In this regard, we developed and studied a novel ERα degrader, which is a PROTAC-like SERD named 17e." [PMID:36905762]; developer: "Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Bayi Road, Wuhan, Hubei 430072, China." [PMID:36905762]; modality: "In this regard, we developed and studied a novel ERα degrader, which is a PROTAC-like SERD named 17e." [PMID:36905762]; stage: "We found that compound 17e can inhibit the growth of BC both in vitro and in vivo and induce the cell cycle arrest of BC." [PMID:36905762]
02
Targets
ESR1 (ERα)
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