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wumeiwan jiawei fang
- Development stage
- Phase 3
- Lead developer
- China Academy of Chinese Medical Sciences
- Administration
- Oral
01
Overview
Wumeiwan Jiawei Fang is a modified Traditional Chinese Medicine (TCM) formula derived from the classical Wumeiwan (Mume Pill), which originated in the *Shanghan Lun*. This specific modification is being evaluated by the China Academy of Chinese Medical Sciences for its efficacy and safety in treating idiopathic blepharospasm, a condition characterized by involuntary eyelid closure. The base formula, Wumeiwan, traditionally comprises ten herbs including Mume Fructus, Coptidis Rhizoma, and Aconiti Lateralis Radix Praeparata, and is used in TCM to address complex patterns of heat and cold. The "Jiawei" (added flavors) aspect indicates the inclusion of additional medicinal herbs intended to enhance the formula's ability to extinguish "internal wind" and relax muscle spasms, aligning with TCM therapeutic principles for movement disorders.
- Other names
- Jing Fang Wu Mei Wan Jiawei FangModified Wumei PillWumeiwan Jiawei
02
Targets
NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)
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