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Wushen Decoction
- Development stage
- Phase 2
- Lead developer
- Binzhou Hospital of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Wushen Decoction is a Traditional Chinese Medicine (TCM) herbal formula currently under clinical investigation for the treatment of acute gouty arthritis. Developed and studied by the Binzhou Hospital of Traditional Chinese Medicine, the decoction is typically composed of multiple botanical ingredients intended to clear heat, resolve dampness, and alleviate pain. Its therapeutic effects are characterized by the reduction of inflammatory biomarkers and the lowering of serum uric acid levels. Network pharmacology studies suggest that Wushen Decoction may act by modulating multi-target pathways involved in the inflammatory response and urate metabolism, providing a potential alternative or adjunct to standard treatments like colchicine.
- Other names
- Wushen TangWu-Shen Decoction
02
Targets
IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)XO (Xanthine Oxidoreductase)TNFA (Tumor necrosis factor alpha (soluble))
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