Drug intelligence / Profile preview

Wuwei Xiaodu granules

Development stage
Unknown
Lead developer
Reyoung Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

Wuwei Xiaodu granules (also known as Wuwei Xiaodu Yin granules) is a traditional Chinese medicine (TCM) formulation derived from the classical Qing Dynasty formula "Wuwei Xiaodu Yin" (Five-Ingredient Decoction to Eliminate Toxin), first recorded in the "Yi Zong Jin Jian" (Golden Mirror of Medicine, 1742). It is composed of five heat-clearing and detoxifying herbs: Jin Yin Hua (*Lonicerae Flos*), Ye Ju Hua (*Chrysanthemi Indici Flos*), Pu Gong Ying (*Taraxaci Herba*), Zi Hua Di Ding (*Herba Violae*), and Tian Kui Zi (*Semiaquilegiae Radix*). The formulation is primarily indicated for clearing heat, resolving toxicity, cooling blood, and reducing swelling. It is widely used to treat acute inflammatory skin conditions such as boils, carbuncles, deep-rooted pustules, mastitis, and early-stage abscesses characterized by localized redness, swelling, heat, and pain. In July 2026, Reyoung Pharmaceutical's "Wuwei Xiaodu Yin granules" became the first classic-formula TCM product of its kind to be approved by China's National Medical Products Administration (NMPA) under the Class 3.1 registration pathway for ancient classical formulas.

Brand names
ActiveHerbKang ShouNature's Green
Other names
Five-Ingredient Decoction to Eliminate ToxinWu Wei Xiao Du YinWuwei Xiaodu decoctionWuwei Xiaodu Yin granules五味消毒饮五味消毒饮颗粒五味消毒颗粒

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