Wuzhi Drop Pills

Wuzhi Drop Pills is a traditional Chinese medicine (TCM) preparation derived from the ethanol extract of *Schisandra sphenanthera*. It is officially approved in China for the treatment of elevated alanine aminotransferase (ALT) levels associated with chronic hepatitis and other forms of liver injury. The formulation contains dibenzocyclooctadiene lignans, such as schisandrin A, B, and C, which exhibit potent hepatoprotective and antioxidant properties. In clinical practice, Wuzhi Drop Pills is frequently utilized as an adjuvant therapy in organ transplant recipients. It acts as a significant inhibitor of the cytochrome P450 3A (CYP3A) enzyme system, which reduces the metabolism of immunosuppressants like tacrolimus and cyclosporine A, thereby increasing their blood concentrations and allowing for lower therapeutic dosing.

Brand names

Wuzhi Drop Pills

Other names

Wu Zhi Di Wan五酯滴丸Wuzhi capsulesSchisandra sphenanthera extract