Drug intelligence / Profile preview

X-Seb T Plus

Development stage
Unknown
Lead developer
Baker Cummins
Modality
Small Molecules
Administration
Topical
01

Overview

X-Seb T Plus is a topical medicated shampoo formulated with a combination of coal tar and salicylic acid, primarily indicated for the management of inflammatory and scaling scalp conditions such as dandruff, seborrheic dermatitis, and psoriasis. Coal tar acts as a keratoplastic agent that slows the rapid proliferation of skin cells and reduces inflammation and itching, likely through the activation of the aryl hydrocarbon receptor (AhR) and the inhibition of DNA synthesis. Salicylic acid serves as a keratolytic agent, facilitating the removal of excess scales by dissolving the intercellular matrix in the stratum corneum. This dual-action approach addresses both the underlying cellular hyperproliferation and the visible scaling associated with chronic scalp disorders.

Brand names
X-Seb T Plus
Other names
X-Seb T Plus Shampoocoal tar + salicylic acid shampoo
02

Targets

AHR (Aryl hydrocarbon receptor)DNA

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