Drug intelligence / Profile preview

X92001666

Development stage
Unknown
Lead developer
Oystershell
Administration
Topical
01

Overview

X92001666 is a water-soluble topical lotion developed by Oystershell NV for the treatment of head lice (*Pediculus humanus capitis*). Marketed under the brand name Elimax, the product utilizes a physical mechanism of action, primarily suffocation, to eliminate lice and their eggs (nits). Unlike traditional pediculicides that contain neurotoxic insecticides such as pyrethrins or malathion, X92001666 blocks the respiratory spiracles of the lice, leading to hypoxia and death. The formulation is specifically designed to be water-soluble, allowing it to be applied to dry hair and easily rinsed out with standard shampoo, which distinguishes it from traditional oil-based suffocation agents like dimethicone. Clinical studies, including a randomized comparative trial against pyrethrin-based RID shampoo, have evaluated its efficacy and safety in pediatric and adult populations.

Brand names
Elimax
Other names
water-soluble head lice suffocation product

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